Cantharidin and Cantharidin Plus
Cantharidin Topical Solution is a liquid vesicant medication comprised primarily of cantharidin and acetone. Cantharidin is a chemical derived from the secretions of one of several different types of blister beetles. When applied to the skin Cantharidin causes blister formation.
Cantharidin from Edge Pharma is a direct replacement for Canthacur. Due to compounding pharmacy regulations, US-based practices cannot purchase non-patient specific office use Canthacur from Canadian-based pharmacies. Cantharidin also cannot be purchased from traditional (503A) compounding pharmacies for office use, since these facilities do not maintain the proper process controls and undergo the required testing to ensure the product is safe for office use. Cantharidin from Edge allows practices to both be in compliance, as well as be secure the product is made in an FDA registered and inspected outsourcing facility.
Edge Pharma offers two formulations of Cantharidin Topical Solution to qualified practitioners in a 10 ml glass multi-dose vial without requiring patient names. Our online system makes ordering quick and easy.
Cantharidin Topical Solution
- Cantharidin 0.7%
Cantharidin Plus Topical Solution
- Cantharidin 1.0%
- Salicylic Acid 30.0%
- Podophyllum Resin 5.0%
Just fill in the simple form to setup an account with Edge. Cantharidin Topical Solution can be ordered in quantities as low as two bottles. Quantity discounts are available, as well as discounts for monthly subscriptions.
1) Moed, Lisa, Tor A. Shwayder, and Mary Wu Chang. "Cantharidin Revisited: A Blistering Defense of an Ancient Medicine." Archives of Dermatology 137.10 (2001): 1357-1360.
"When cantharidin is used appropriately, complications are exceedingly rare."
"There is no scarring with proper use."
2) Kartal Durmazlar, Selda Pelinxs, Damla Atacan, and Fatma Eskioglu. "Cantharidin treatment for recalcitrant facial flat warts: a preliminary study." Journal of Dermatological Treatment 20.2 (2009): 114-119.
"All the patients were clinically cured within 16 weeks and the number of required sessions for complete clearance was 2.6 ± 1.18."
"Cantharidin therapy was well tolerated, with mild adverse events related to skin. Conclusion: Cantharidin is safe and effective when applied to flat warts without occlusion for 4–6 hours every 3 weeks till clear."
3) Torbeck, Richard; Pan, Michael; de Moll, Ellen; & Levitt, Jacob. "Cantharidin: A Comprehensive Review of the Clinical Literature." Dermatology Online Journal, 20(6). doj_22861. (2014) Retrieved from: http://escholarship.org/uc/item/45r512w0
"The incidence of adverse effects associated with cantharidin for MC are: blistering (92%), erythema (37%), pain (14%), burning (10%), and pruritus (6%). Despite these adverse effects, 95% of parents polled stated they would choose cantharidin for MC treatment."
"Cantharidin has been used to manage flat, palpebral, plantar, periungual, and subungual warts in an office setting."
"When compared to cryotherapy, cantharidin required fewer treatments to achieve resolution (4.14 vs. 2.71). The rate of recurrence with cantharidin treatment was low, with no recurrences at six months in 144 patients with flat warts and only 1 recurrence at 1 year for digital/periungual warts."
"Potential novel applications of cantharidin include application in acquired perforating dermatosis, acute herpes zoster, and leishmaniasis."
4) López López, D., Vilar Fernández, J. M., Losa Iglesias, M. E., Álvarez Castro, C., Romero Morales, C., García Sánchez, M. M. and Becerro de Bengoa Vallejo, R. (2016), "Safety and Effectiveness of Cantharidin–Podophylotoxin–Salicylic Acid in the Treatment of Recalcitrant Plantar Warts. Dermatologic Therapy, 29: 269–273. doi:10.1111/dth.12356
"All patients reported treatment, supporting our results that CPS [Cantharidin-Podophylotoxin-Salicylic Acid] is a safe and efficacious treatment modality for RPW and should be considered when symptomatic infection necessitates treatment."
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